ATG7 antibody

Catalog No. ABIN7880011

The Rabbit Polyclonal anti-ATG7 antibody (ABIN7880011) specifically detects ATG7 in WB, IHC (p) and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ATG7 antibody (ABIN7880011)

Target: ATG7 (ATG7 Autophagy Related 7 (ATG7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-ATG7 Antibody

Purpose: ATG7 Antibody

Sequence: HELTQKKLNE YRLDEAPKDI K

Purification: Affinity purified

Immunogen: Amino acids HELTQKKLNEYRLDEAPKDIK from the human protein were used as the immunogen for the ATG7 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ATG7 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ATG7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ATG7

Target: ATG7 (ATG7 Autophagy Related 7 (ATG7))

Alternative Name: ATG7

Background: Autophagy related 7 is a protein in humans encoded by ATG7 gene. It is mapped to 3p25.3. This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants.

UniProt: O95352

Pathways: Response to Water Deprivation, Autophagy