ATL1 antibody

Catalog No. ABIN7880014

The Rabbit Polyclonal anti-ATL1 antibody (ABIN7880014) specifically detects ATL1 in WB, IHC (p) and FACS. The antibody is reactive with Human samples.

Quick Overview for ATL1 antibody (ABIN7880014)

Target: ATL1 (Atlastin GTPase 1 (ATL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-ATL1 Antibody

Purpose: Atlastin-1 Antibody / ATL1 / SPG3A

Sequence: DKPFLAPNDL QTKHLQ

Purification: Antigen affinity purified

Immunogen: Amino acids DKPFLAPNDLQTKHLQ from the human protein were used as the immunogen for the Atlastin-1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Atlastin-1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Atlastin-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ATL1

Target: ATL1 (Atlastin GTPase 1 (ATL1))

Alternative Name: Atlastin-1

Background: Atlastin, or Atlastin-1, is a protein that in humans is encoded by the ATL1 gene. The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.

UniProt: Q8WXF7