Recombinant BAG1 antibody

Catalog No. ABIN7880055

The Rabbit Monoclonal anti-BAG1 antibody is suitable to detect BAG1 in samples from Human, Mouse and Rat. It has been validated for WB, IF and IHC (p).

Quick Overview for Recombinant BAG1 antibody (ABIN7880055)

Target: BAG1 (BCL2-Associated Athanogene (BAG1))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This BAG1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 28B16

Product Details anti-BAG1 Antibody

Purpose: BAG family molecular chaperone regulator 1 Antibody / BAG1

Purification: Affinity chromatography

Immunogen: A synthetic peptide derived from human Bag1 was used as the immunogen for the BAG family molecular chaperone regulator 1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the BAG family molecular chaperone regulator 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the BAG family molecular chaperone regulator 1 antibody at -20oC.

Target Details for BAG1

Target: BAG1 (BCL2-Associated Athanogene (BAG1))

Alternative Name: BAG family molecular chaperone regulator 1

Background: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70. [UniProt]

UniProt: Q99933