BNP antibody

Catalog No. ABIN7880095

The Mouse Monoclonal anti-BNP antibody (Clone NPPB-4493) (ABIN7880095) specifically detects BNP in IHC (p). The antibody is reactive with Human samples.

Quick Overview for BNP antibody (ABIN7880095)

Target: BNP (Brain Natriuretic Peptide (BNP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BNP antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: NPPB-4493

Product Details anti-BNP Antibody

Purpose: BNP Antibody / Brain Natriuretic Peptide / NPPB (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A recombinant protein fragment was used as the immunogen for the BNP antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the BNP antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the BNP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for BNP

Target: BNP (Brain Natriuretic Peptide (BNP))

Alternative Name: BNP

Background: Natriuretic peptides comprise a family of three structurally related molecules: atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP) and C-type natriuretic peptide (CNP). ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. These peptides possess potent natriuretic, diuretic and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control. ANP, BNP and CNP are highly homologous within the 17-residue ring structure formed by an intramolecular disulfide linkage. The genes which encode for ANP and BNP map to human chromosome 1p36.22. The gene which encodes for CNP maps to human chromosome 2q37.1.

UniProt: P16860

Pathways: Hormone Activity