CA3 antibody

Catalog No. ABIN7880166

The Mouse Monoclonal anti-CA3 antibody is suitable to detect CA3 in samples from Human. It has been validated for IHC (p).

Quick Overview for CA3 antibody (ABIN7880166)

Target: CA3 (Carbonic Anhydrase III (CA3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CA3 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CA3-7884

Product Details anti-CA3 Antibody

Purpose: Carbonic Anhydrase 3 Antibody / CA3

Purification: Protein A/G affinity

Immunogen: A recombinant fragment of human CA3 protein was used as the immunogen for the Carbonic Anhydrase 3 antibody.

Isotype: IgG2, kappa

Application Details

Application Notes: Optimal dilution of the Carbonic Anhydrase 3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Carbonic Anhydrase 3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CA3

Target: CA3 (Carbonic Anhydrase III (CA3))

Alternative Name: Carbonic Anhydrase 3

Background: Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. CAs are involved in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric juice. They show extensive diversity in distribution and in their subcellular localization. CA III (carbonic anhydrase III), also known as Car3 or CA3, is a 260 amino acid cytoplasmic protein that is specifically expressed in muscle. Belonging to the a-carbonic anhydrase family, CA III is activated by proton donors such as imidazole and dipeptide histidylhistidine, and is inhibited by coumarins and sulfonamide derivatives such as acetazolamide.

UniProt: P07451