CTNND1 antibody

Catalog No. ABIN7880196

The Rabbit Monoclonal anti-CTNND1 antibody is suitable to detect CTNND1 in samples from Human. It has been validated for WB.

Quick Overview for CTNND1 antibody (ABIN7880196)

Target: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CTNND1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: GI-3

Product Details anti-CTNND1 Antibody

Purpose: p120 Catenin Antibody / CTNND1

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Catenin delta 1 / p120 Catenin / CTNND1 was used as the immunogen for the p120 Catenin antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the p120 Catenin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the p120 Catenin antibody at -20oC.

Target Details for CTNND1

Target: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Alternative Name: p120 Catenin

Background: P120 Catenin binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). Associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage. [UniProt]

UniProt: O60716

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling