CEBPE antibody

Catalog No. ABIN7880217

The Mouse Monoclonal anti-CEBPE antibody is suitable to detect CEBPE in samples from Human. It has been validated for IF and FACS.

Quick Overview for CEBPE antibody (ABIN7880217)

Target: CEBPE (CCAAT/enhancer Binding Protein (C/EBP), epsilon (CEBPE))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CEBPE antibody is un-conjugated

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Grade: Carrier-free

Clone: PCRP-CEBPE-1G12

Product Details anti-CEBPE Antibody

Purpose: C/EBP epsilon Antibody / CEBPE (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant human protein was used as the immunogen for the C/EBP epsilon antibody.

Isotype: IgG2a

Application Details

Application Notes: Optimal dilution of the C/EBP epsilon antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the C/EBP epsilon antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CEBPE

Target: CEBPE (CCAAT/enhancer Binding Protein (C/EBP), epsilon (CEBPE))

Alternative Name: C/EBP epsilon

Background: The transcription factor C/EBP Alpha (CCAAT-enhancer binding protein) is a heatstable, sequence-specific DNA-binding protein first purified from rat liver nuclei that binds avidly to several different cis-regulatory DNA sequences commonly associated with viral and cellular genes transcribed by RNA polymerase II. C/EBP Alpha regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP Alpha uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of amphipathic Alpha helices termed the leucine zipper. Highly basic polypeptide regions emerge from the zipper to form a linked set of DNA contact surfaces. C/EBP Alpha appears to function exclusively in terminally differentiated, growth-arrested cells. Additional family members include C/EBP beta, C/EBP gamma, C/EBP delta and C/EBP epsilon, all of which exhibit similar DNA-binding specificities and affinities to C/EBP Alpha. Furthermore, C/EBP beta and C/EBP delta readily form heterodimers both with each other as well as with C/EBP Alpha.

UniProt: Q15744

Pathways: Cellular Response to Molecule of Bacterial Origin