DC-SIGN/CD209 antibody

Catalog No. ABIN7880256

The Mouse Monoclonal anti-DC-SIGN/CD209 antibody is suitable to detect DC-SIGN/CD209 in samples from Human. It has been validated for FACS.

Quick Overview for DC-SIGN/CD209 antibody (ABIN7880256)

Target: DC-SIGN/CD209 (CD209) (CD209)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DC-SIGN/CD209 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Grade: Carrier-free

Clone: C209-6774

Product Details anti-DC-SIGN/CD209 Antibody

Purpose: CD209 Antibody / DC-SIGN (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A recombinant human DC-SIGN/CD209 protein fragment was used as the immunogen for the CD209 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the CD209 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the CD209 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for DC-SIGN/CD209

Target: DC-SIGN/CD209 (CD209) (CD209)

Alternative Name: CD209

Background: DC-SIGN/CD209 is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.

UniProt: Q9NNX6