DC-SIGN/CD209 antibody

Catalog No. ABIN7880257

The Mouse Monoclonal anti-DC-SIGN/CD209 antibody (Clone C209-6774) (ABIN7880257) specifically detects DC-SIGN/CD209 in FACS. The antibody is reactive with Human samples.

Quick Overview for DC-SIGN/CD209 antibody (ABIN7880257)

Target: DC-SIGN/CD209 (CD209) (CD209)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DC-SIGN/CD209 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: C209-6774

Product Details anti-DC-SIGN/CD209 Antibody

Purpose: CD209 Antibody / DC-SIGN

Purification: Protein A/G affinity

Immunogen: A recombinant human DC-SIGN/CD209 protein fragment was used as the immunogen for the CD209 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the CD209 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CD209 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for DC-SIGN/CD209

Target: DC-SIGN/CD209 (CD209) (CD209)

Alternative Name: CD209

Background: DC-SIGN/CD209 is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.

UniProt: Q9NNX6