Recombinant CXCR5 antibody

Catalog No. ABIN7880401

The Rabbit Monoclonal anti-CXCR5 antibody (Clone 20C58) (ABIN7880401) specifically detects CXCR5 in WB and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Recombinant CXCR5 antibody (ABIN7880401)

Target: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CXCR5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 20C58

Product Details anti-CXCR5 Antibody

Purpose: CXCR5 Antibody | C-X-C chemokine receptor type 5

Purification: Affinity chromatography

Immunogen: A peptide sequence specific to C-X-C chemokine receptor type 5 was used as the immunogen for the CXCR5 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the CXCR5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the CXCR5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for CXCR5

Target: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Alternative Name: CXCR5

Background: C-X-C chemokine receptor type 5 (CXCR5) is a G protein-coupled receptor primarily expressed on B cells and certain subsets of T cells. It binds the chemokine CXCL13, guiding lymphocyte migration to B cell follicles within secondary lymphoid organs. CXCR5 plays a crucial role in lymphoid tissue organization and immune surveillance.

CXCR5 is essential for germinal center formation and effective humoral immune responses. Altered expression or function of CXCR5 has been associated with autoimmune diseases, immunodeficiencies, and certain cancers, making it an important focus in immunology and oncology research.

Using a high-quality CXCR5 antibody enables sensitive detection in applications such as flow cytometry, immunohistochemistry, and western blot. A CXCR5 antibody from NSJ Bioreagents ensures reproducibility and accuracy in studies involving immune cell trafficking, germinal center biology, and disease pathogenesis. Selecting the right CXCR5 antibody is key for obtaining reliable and consistent research results.

UniProt: P32302