Claudin 1 antibody

Catalog No. ABIN7880443

The Rabbit Monoclonal anti-Claudin 1 antibody (Clone ABEH-3) (ABIN7880443) specifically detects Claudin 1 in WB. The antibody is reactive with Human samples.

Quick Overview for Claudin 1 antibody (ABIN7880443)

Target: Claudin 1 (CLDN1)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Claudin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: ABEH-3

Product Details anti-Claudin 1 Antibody

Purpose: CLDN1 Antibody / Claudin 1

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Claudin 1 / CLDN1 was used as the immunogen for the CLDN1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the CLDN1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the CLDN1 antibody at -20oC.

Target Details for Claudin 1

Target: Claudin 1 (CLDN1)

Alternative Name: CLDN1

Background: Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. [UniProt]

UniProt: O95832

Pathways: Cell-Cell Junction Organization, Hepatitis C