Claudin 3 antibody

Catalog No. ABIN7880447

This Rabbit Polyclonal antibody specifically detects Claudin 3 in WB, IF, IHC (p) and FACS. It exhibits reactivity toward Human.

Quick Overview for Claudin 3 antibody (ABIN7880447)

Target: Claudin 3 (CLDN3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-Claudin 3 Antibody

Purpose: CLDN3 Antibody / Claudin 3

Sequence: REKKYTATKV VYSAPRST

Purification: Affinity purified

Immunogen: Amino acids REKKYTATKVVYSAPRST from the human protein were used as the immunogen for the CLDN3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the CLDN3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the CLDN3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Claudin 3

Target: Claudin 3 (CLDN3)

Alternative Name: CLDN3

Background: Claudin 3, also known as CLDN3, is a protein which in humans is encoded by the CLDN3 gene. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.

UniProt: O15551

Pathways: Hepatitis C