Recombinant CIRBP antibody

Catalog No. ABIN7880468

This Rabbit Monoclonal antibody specifically detects CIRBP in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant CIRBP antibody (ABIN7880468)

Target: CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CIRBP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 26C38

Product Details anti-CIRBP Antibody

Purpose: CIRBP Antibody / Cold-inducible RNA-binding protein

Purification: Affinity chromatography

Immunogen: A peptide sequence specific to Cold-inducible RNA-binding protein was used as the immunogen for the CIRBP antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the CIRBP antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the CIRBP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for CIRBP

Target: CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

Alternative Name: CIRBP

Background: Cold-inducible RNA-binding protein (CIRBP) is a stress-response protein that binds to RNA and modulates mRNA stability and translation. It is upregulated in response to mild hypothermia, ultraviolet radiation, and other cellular stressors, helping to regulate gene expression under challenging environmental conditions.

CIRBP plays roles in cell proliferation, circadian rhythm regulation, and protection against apoptosis. It has been implicated in processes such as spermatogenesis, inflammation, and tumor progression. Altered CIRBP expression or function can influence cellular stress adaptation and disease development, making it a valuable target for molecular and biomedical research.

Using a high-quality CIRBP antibody allows precise detection in applications such as western blot, immunohistochemistry, and immunofluorescence. A CIRBP antibody from NSJ Bioreagents ensures reproducibility and sensitivity for studies in stress response biology, RNA regulation, and disease mechanisms. Selecting the right CIRBP antibody is essential for generating consistent and reliable experimental results.

UniProt: Q14011

Pathways: Ribonucleoprotein Complex Subunit Organization