C4A antibody

Catalog No. ABIN7880504

This Rabbit Monoclonal antibody specifically detects C4A in WB. It exhibits reactivity toward Human.

Quick Overview for C4A antibody (ABIN7880504)

Target: C4A (C4a) (Complement Fragment C4a (C4a))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This C4A antibody is un-conjugated

Application: Western Blotting (WB)

Clone: AFHB-3

Product Details anti-C4A Antibody

Purpose: C4A Antibody / Complement C4A

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human C4A / Complement C4A was used as the immunogen for the C4A antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the C4A antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the C4A antibody at -20oC.

Target Details for C4A

Target: C4A (C4a) (Complement Fragment C4a (C4a))

Alternative Name: C4A

Background: This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain is cleaved to release C4 anaphylatoxin, an antimicrobial peptide and a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. [RefSeq]

UniProt: P0C0L4

Pathways: Complement System