COX IV antibody

Catalog No. ABIN7880568

The Rabbit Monoclonal anti-COX IV antibody is suitable to detect COX IV in samples from Human. It has been validated for WB.

Quick Overview for COX IV antibody (ABIN7880568)

Target: COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This COX IV antibody is un-conjugated

Application: Western Blotting (WB)

Clone: AIC-3

Product Details anti-COX IV Antibody

Purpose: COX IV Antibody / COX4I1

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human COX IV / COX4I1 was used as the immunogen for the COX IV antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the COX IV antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the COX IV antibody at -20oC.

Target Details for COX IV

Target: COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))

Alternative Name: COX IV

Background: Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. [RefSeq]

UniProt: P13073

Pathways: Proton Transport