DDX58 antibody

Catalog No. ABIN7880607

The Rabbit Monoclonal anti-DDX58 antibody is suitable to detect DDX58 in samples from Human. It has been validated for WB.

Quick Overview for DDX58 antibody (ABIN7880607)

Target: DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This DDX58 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: ACEA-4

Product Details anti-DDX58 Antibody

Purpose: RIG-I Antibody / DDX58

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human RIG-I was used as the immunogen for the RIG-I antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the RIG-I antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the RIG-I antibody at -20oC.

Target Details for DDX58

Target: DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

Alternative Name: RIG-I

Background: Retinoic acid inducible gene I (RIG-I) is a 925 amino acid, interferon-inducible cellular DExD/H box RNA helicase that activates type I interferon (IFN), an important effector of the innate immune system that is sensitive to these dsRNA viruses. dsRNA is normally present in very low quantities in cells, so when a virus is present, the elevated levels of dsRNA act as a sign telling RIG-I to activate the production of IFN.

UniProt: O95786

Pathways: Activation of Innate immune Response, Hepatitis C