Density Regulated Protein antibody

Catalog No. ABIN7880611

The Mouse Monoclonal anti-Density Regulated Protein antibody (Clone 1542CT106-51-79) (ABIN7880611) specifically detects Density Regulated Protein in WB, IF, IHC (p) and FACS. The antibody is reactive with Human samples.

Quick Overview for Density Regulated Protein antibody (ABIN7880611)

Target: Density Regulated Protein (DENR) (Density-Regulated Protein (DENR))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Density Regulated Protein antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: 1542CT106-51-79

Product Details anti-Density Regulated Protein Antibody

Purpose: Density Regulated Protein Antibody / DENR

Purification: Protein G affinity

Immunogen: Recombinant human protein was used as the immunogen for the Density Regulated Protein antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Density Regulated Protein antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Density Regulated Protein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Density Regulated Protein

Target: Density Regulated Protein (DENR) (Density-Regulated Protein (DENR))

Alternative Name: Density Regulated Protein

Background: May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation, promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.

UniProt: O43583