DKK2 antibody

Catalog No. ABIN7880625

The Mouse Monoclonal anti-DKK2 antibody is suitable to detect DKK2 in samples from Human and Mouse. It has been validated for WB.

Quick Overview for DKK2 antibody (ABIN7880625)

Target: DKK2 (Dickkopf 2 Homolog (DKK2))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This DKK2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 1833CT856-7-20

Product Details anti-DKK2 Antibody

Purpose: DKK2 Antibody

Purification: Protein G purified

Immunogen: Recombinant human DKK2 was used as the immunogen for the DKK2 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the DKK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the DKK2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for DKK2

Target: DKK2 (Dickkopf 2 Homolog (DKK2))

Alternative Name: DKK2

Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity). [UniProt]

UniProt: Q9UBU2

Pathways: WNT Signaling