Recombinant DLAT antibody

Catalog No. ABIN7880628

The Rabbit Monoclonal anti-DLAT antibody is suitable to detect DLAT in samples from Human, Mouse and Rat. It has been validated for WB, IF and IHC (p).

Quick Overview for Recombinant DLAT antibody (ABIN7880628)

Target: DLAT (Dihydrolipoyl Transacetylase (DLAT))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This DLAT antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 23D09

Product Details anti-DLAT Antibody

Purpose: PDC-E2 Antibody / Pyruvate Dehydrogenase E2

Purification: Affinity chromatography

Immunogen: A peptide sequence specific to Pyruvate Dehydrogenase E2 was used as the immunogen for the PDC-E2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PDC-E2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PDC-E2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for DLAT

Target: DLAT (Dihydrolipoyl Transacetylase (DLAT))

Alternative Name: PDC-E2

Background: Pyruvate dehydrogenase E2 (PDC-E2) is the dihydrolipoamide acetyltransferase component of the pyruvate dehydrogenase complex, a key mitochondrial enzyme complex linking glycolysis to the citric acid cycle. PDC-E2 catalyzes the transfer of an acetyl group from pyruvate to coenzyme A, producing acetyl-CoA for cellular energy metabolism.

PDC-E2 is essential for efficient carbohydrate oxidation and energy production. It is also the primary autoantigen recognized in primary biliary cholangitis (PBC), an autoimmune liver disease, making it important in both metabolic and immunological research.

Using a high-quality PDC-E2 antibody enables accurate detection in applications such as western blot, immunohistochemistry, and ELISA. A PDC-E2 antibody from NSJ Bioreagents ensures sensitivity and reproducibility for studies involving mitochondrial function, metabolic pathways, and autoimmune disease. Selecting the right PDC-E2 antibody is critical for producing consistent and reliable research results.

UniProt: P10515