DPYSL2 antibody

Catalog No. ABIN7880629

The Rabbit Polyclonal anti-DPYSL2 antibody (ABIN7880629) specifically detects DPYSL2 in WB and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for DPYSL2 antibody (ABIN7880629)

Target: DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPYSL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-DPYSL2 Antibody

Purpose: CRMP2 Antibody / DPYSL2

Purification: Antigen affinity purified

Immunogen: Amio acids KDRFQLTDCQIYEVLSV were used as the immunogen for the CRMP2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the CRMP2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the CRMP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for DPYSL2

Target: DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))

Alternative Name: CRMP2

Background: Dihydropyrimidinase-related protein 2, also called Collapsin response mediator protein 2 (CRMP2), is an enzyme that in humans is encoded by the DPYSL2 gene. This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

UniProt: Q16555

Pathways: Regulation of Cell Size