Doublecortin antibody

Catalog No. ABIN7880653

The Rabbit Monoclonal anti-Doublecortin antibody (Clone AOAD-4) (ABIN7880653) specifically detects Doublecortin in WB. The antibody is reactive with Human and Rat samples.

Quick Overview for Doublecortin antibody (ABIN7880653)

Target: Doublecortin (DCX)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Doublecortin antibody is un-conjugated

Application: Western Blotting (WB)

Clone: AOAD-4

Product Details anti-Doublecortin Antibody

Purpose: Doublecortin Antibody / DBCN / DCX

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Doublecortin / DCX was used as the immunogen for the Doublecortin antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Doublecortin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the Doublecortin antibody at -20oC.

Target Details for Doublecortin

Target: Doublecortin (DCX)

Alternative Name: Doublecortin

Background: The neuronal migration protein Doublecortin is a microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration. [UniProt]

UniProt: O43602