EHD3 antibody

Catalog No. ABIN7880673

The Rabbit Polyclonal anti-EHD3 antibody is suitable to detect EHD3 in samples from Human, Mouse, Rat and Monkey. It has been validated for WB, FACS, IHC (p) and IF.

Quick Overview for EHD3 antibody (ABIN7880673)

Target: EHD3 (EH-Domain Containing 3 (EHD3))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EHD3 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-EHD3 Antibody

Purpose: EHD3 Antibody / EH domain-containing protein 3

Sequence: NELPAHLLPP SKRKVAE

Purification: Antigen affinity purified

Immunogen: Amino acids NELPAHLLPPSKRKVAE were used as the immunogen for the EHD3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the EHD3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the EHD3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for EHD3

Target: EHD3 (EH-Domain Containing 3 (EHD3))

Alternative Name: EHD3

Background: Eps15 homology domain-containing protein 3, abbreviated as EDH3 and also known as PAST3, is a protein encoded by the EHD3 gene. The Eps15 homology (EH) domain-containing protein family consists of four members, EHD1, EHD2, EHD3, and EHD4. The chromosomal locations of the human EHD genes are as follows: EHD1 maps to 11q13, EHD2 maps to 19q13.3, EHD3 maps to 2p21, and EHD4 maps to 15q11.1 (1-3). The encoded proteins of all EHD family members contain multiple conserved regions, which include an amino-terminal nucleotide-binding consensus site, a bipartite nuclear localization signal, and a carboxy-terminal EH protein-binding domain with an EF-hand motif (3,4). EHD1 is ubiquitously expressed with increased expression in testis (2,3). EHD2, EHD3, and EHD4 have more specific expression with EHD2 highly expressed in heart, EHD3 expressed in brain, kidney, liver, placenta, ovary, and heart, and EHD4 expressed in heart, placenta, and pancreas (1,5,6). The EHD proteins may participate in ligand-induced endocytosis (3-5).

UniProt: Q9NZN3