ERVW-1 antibody

Catalog No. ABIN7880679

The Rabbit Polyclonal anti-ERVW-1 antibody is suitable to detect ERVW-1 in samples from Human. It has been validated for WB.

Quick Overview for ERVW-1 antibody (ABIN7880679)

Target: ERVW-1 (Endogenous Retrovirus Group W, Member 1 (ERVW-1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERVW-1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ERVW-1 Antibody

Purpose: ERVW-1 Antibody / Syncytin-1

Sequence: YYVNQSGIVT EKVKEIRDRI QRRAEELRNT

Purification: Antigen affinity

Immunogen: Amino acids YYVNQSGIVTEKVKEIRDRIQRRAEELRNT of human ERVW-1 were used as the immunogen for the ERVW-1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ERVW-1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ERVW-1 antibody antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ERVW-1

Target: ERVW-1 (Endogenous Retrovirus Group W, Member 1 (ERVW-1))

Alternative Name: ERVW-1

Background: ERVW-1 is also known as ERVWE1 and Syncytin-1. The human ERVWE1 locus is derived from a human endogenous retrovirus-W (HERV-W) provirus located on chromosome 7. This provirus has inactivating mutations in the gag and pol genes, but the envelope glycoprotein gene has been selectively preserved. The product of this gene, syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.

UniProt: Q9UQF0