Recombinant EPX antibody

Catalog No. ABIN7880693

This Rabbit Monoclonal antibody specifically detects EPX in IF, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant EPX antibody (ABIN7880693)

Target: EPX (Eosinophil Peroxidase (EPX))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This EPX antibody is un-conjugated

Application: Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: EPX-3908R

Product Details anti-EPX Antibody

Purpose: Recombinant EPX Antibody / Eosinophil Peroxidase

Purification: Protein A affinity chromatography

Immunogen: Human eosinophils from a patient with hypereosinophilic syndrome were used as the immunogen for the EPX antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the recombinant EPX antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant EPX antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for EPX

Target: EPX (Eosinophil Peroxidase (EPX))

Alternative Name: EPX

Background: Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO).

UniProt: P11678