ESRRA antibody

Catalog No. ABIN7880742

The Rabbit Monoclonal anti-ESRRA antibody is suitable to detect ESRRA in samples from Human. It has been validated for WB.

Quick Overview for ESRRA antibody (ABIN7880742)

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ESRRA antibody is un-conjugated

Application: Western Blotting (WB)

Clone: EIO-5

Product Details anti-ESRRA Antibody

Purpose: ESRRA Antibody / Estrogen-related receptor alpha

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human ESRRA / Estrogen-related receptor alpha was used as the immunogen for the ESRRA antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ESRRA antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the ESRRA antibody at -20oC.

Target Details for ESRRA

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Alternative Name: ESRRA

Background: The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. Alternatively spliced transcript variants have been found for this gene. [RefSeq]

UniProt: P11474

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha