EIF4E antibody

Catalog No. ABIN7880753

This Rabbit Monoclonal antibody specifically detects EIF4E in WB. It exhibits reactivity toward Human.

Quick Overview for EIF4E antibody (ABIN7880753)

Target: EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This EIF4E antibody is un-conjugated

Application: Western Blotting (WB)

Clone: AFHI-5

Product Details anti-EIF4E Antibody

Purpose: EIF4E Antibody

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human EIF4E was used as the immunogen for the EIF4E antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the EIF4E antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the EIF4E antibody at -20oC.

Target Details for EIF4E

Target: EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))

Alternative Name: EIF4E

Background: EIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types.

UniProt: P06730

Pathways: BCR Signaling