XPO1 antibody

Catalog No. ABIN7880757

The Rabbit Monoclonal anti-XPO1 antibody is suitable to detect XPO1 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for XPO1 antibody (ABIN7880757)

Target: XPO1 (Exportin 1 (XPO1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This XPO1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: AEFD-24

Product Details anti-XPO1 Antibody

Purpose: CRM1 Antibody / XPO1 / Exportin 1

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human CRM1 / XPO1 was used as the immunogen for the CRM1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the CRM1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the CRM1 antibody at -20oC.

Target Details for XPO1

Target: XPO1 (Exportin 1 (XPO1))

Alternative Name: CRM1

Background: Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP). Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins.

UniProt: O14980

Pathways: M Phase