F11R antibody

Catalog No. ABIN7880760

The Rabbit Polyclonal anti-F11R antibody is suitable to detect F11R in samples from Human. It has been validated for WB, FACS and IF.

Quick Overview for F11R antibody (ABIN7880760)

Target: F11R (F11 Receptor (F11R))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This F11R antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-F11R Antibody

Purpose: F11R Antibody / JAM-A

Sequence: RVEWKFDQGD TTRLVCYNNK

Purification: Affinity purified

Immunogen: Amino acids RVEWKFDQGDTTRLVCYNNK from the human protein were used as the immunogen for the F11R antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the F11R antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the F11R antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for F11R

Target: F11R (F11 Receptor (F11R))

Alternative Name: F11R

Background: Junctional adhesion molecule A is a protein that in humans is encoded by the F11R gene. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

UniProt: Q9Y624

Pathways: Cell-Cell Junction Organization