FGA antibody

Catalog No. ABIN7880785

The Mouse Monoclonal anti-FGA antibody (Clone UC45) (ABIN7880785) specifically detects FGA in ELISA, IF and FACS. The antibody is reactive with Human samples.

Quick Overview for FGA antibody (ABIN7880785)

Target: FGA (Fibrinogen alpha Chain (FGA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FGA antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: UC45

Product Details anti-FGA Antibody

Purpose: Fibrinogen Alpha Chain Antibody

Purification: PEG precipitation

Immunogen: Human acute monoblastic leukemia cells were used as the immunogen for the Fibrinogen Alpha Chain antibody.

Isotype: IgM, kappa

Application Details

Application Notes: Optimal dilution of the Fibrinogen Alpha Chain antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the Fibrinogen Alpha Chain antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for FGA

Target: FGA (Fibrinogen alpha Chain (FGA))

Alternative Name: Fibrinogen Alpha Chain

Background: The plasma glycoprotein Fibrinogen is synthesized in the liver and comprises three structurally different subunits. Fibrinogen is important in platelet aggregation, the final step of the coagulation cascade (i.e. the formation of Fibrin) and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Following vascular injury, Fibrinogen is cleaved by Thrombin to form Fibrin, which is the most abundant component of blood clots. The cleavage products of Fibrinogen regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types.

UniProt: P02671