FOXL2 antibody

Catalog No. ABIN7880810

This Mouse Monoclonal antibody specifically detects FOXL2 in ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for FOXL2 antibody (ABIN7880810)

Target: FOXL2 (Forkhead Box L2 (FOXL2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FOXL2 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: PCRP-FOXL2-1B4

Product Details anti-FOXL2 Antibody

Purpose: FOXL2 Antibody / Forkhead box protein L2

Purification: Protein A/G affinity

Immunogen: The protein domain of FOXL2 protein was used as the immunogen for the FOXL2 antibody.

Isotype: IgG2c

Application Details

Application Notes: Optimal dilution of the FOXL2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the FOXL2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for FOXL2

Target: FOXL2 (Forkhead Box L2 (FOXL2))

Alternative Name: FOXL2

Background: FOXL2 is a critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. It prevents trans-differentiation of ovary to testis through transcriptional repression of the sertoli cell-promoting gene SOX9. FOXL2 is mainly expressed in ovary, parathyroid gland and sex cord-stromal tumors. FOXL2 is generally used for diagnosis of sex cord-stromal tumors with Inhibin, Calretinin and SF-1.

UniProt: P58012

Pathways: Nuclear Hormone Receptor Binding, Positive Regulation of Endopeptidase Activity