FTCD antibody

Catalog No. ABIN7880819

This Mouse Monoclonal antibody specifically detects FTCD in WB, FACS and IF. It exhibits reactivity toward Human.

Quick Overview for FTCD antibody (ABIN7880819)

Target: FTCD (Formiminotransferase Cyclodeaminase (FTCD))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FTCD antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: FTCD-357

Product Details anti-FTCD Antibody

Purpose: 58K Golgi protein Antibody / Golgi Marker

Purification: Protein A/G affinity

Immunogen: 58K Golgi protein purified from rat liver was used as the immunogen for the 58K Golgi protein antibody.

Isotype: IgG1

Application Details

Application Notes: Optimal dilution of the 58K Golgi protein antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the 58K Golgi protein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for FTCD

Target: FTCD (Formiminotransferase Cyclodeaminase (FTCD))

Alternative Name: 58K Golgi protein

Background: The antibody recognizes an epitope located on the microtubule-binding peripheral Golgi membrane 58 kDa protein. It is also useful for studies on the effect of microtubule-perturbing agents on the Golgi apparatus.The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively-spliced transcript variants have been found for this gene. Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool. Binds and promotes bundling of vimentin filaments originating from the Golgi.

UniProt: O95954