Recombinant GABARAPL2 antibody

Catalog No. ABIN7880845

The Rabbit Monoclonal anti-GABARAPL2 antibody (Clone 17G90) (ABIN7880845) specifically detects GABARAPL2 in WB and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Recombinant GABARAPL2 antibody (ABIN7880845)

Target: GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This GABARAPL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 17G90

Product Details anti-GABARAPL2 Antibody

Purpose: GABARAPL2 Antibody / Gamma-aminobutyric acid receptor-associated protein-like 2

Purification: Affinity chromatography

Immunogen: A peptide sequence specific to Gamma-aminobutyric acid receptor-associated protein-like 2 was used as the immunogen for the GABARAPL2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the GABARAPL2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the GABARAPL2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for GABARAPL2

Target: GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))

Alternative Name: GABARAPL2

Background: Gamma-aminobutyric acid receptor-associated protein-like 2 (GABARAPL2) is a ubiquitin-like protein involved in autophagy, intracellular trafficking, and receptor transport. It plays a role in the expansion of autophagosomal membranes and the delivery of cargo to lysosomes for degradation. GABARAPL2 also participates in the regulation of GABA receptor trafficking, influencing synaptic transmission.

GABARAPL2 is expressed in various tissues and is linked to cellular processes such as protein turnover, stress responses, and immune regulation. Dysregulation of GABARAPL2 has been associated with neurological disorders, cancer, and other diseases involving impaired autophagy. Studying GABARAPL2 function helps elucidate the molecular mechanisms of protein homeostasis and membrane dynamics.

Using a high-quality GABARAPL2 antibody enables sensitive and specific detection in applications including western blot, immunohistochemistry, and immunofluorescence. A GABARAPL2 antibody from NSJ Bioreagents ensures reproducible results for studies focused on autophagy, protein trafficking, and neurobiology. Selecting the right GABARAPL2 antibody is essential for generating accurate and consistent data in both basic and applied research.

UniProt: P60520

Pathways: Autophagy