GTF2I antibody

Catalog No. ABIN7880865

The Mouse Monoclonal anti-GTF2I antibody is suitable to detect GTF2I in samples from Human. It has been validated for FACS.

Quick Overview for GTF2I antibody (ABIN7880865)

Target: GTF2I (General Transcription Factor III (GTF2I))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GTF2I antibody is un-conjugated

Application: Flow Cytometry (FACS)

Grade: Carrier-free

Clone: PCRP-GTF2I-1A7

Product Details anti-GTF2I Antibody

Purpose: GTF2I Antibody / General transcription factor II-I (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant human protein was used as the immunogen for the GTF2I antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the GTF2I antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the GTF2I antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for GTF2I

Target: GTF2I (General Transcription Factor III (GTF2I))

Alternative Name: GTF2I

Background: Interacts with the basal transcription machinery by coordinating the formation of a multiprotein complex at the C-FOS promoter, and linking specific signal responsive activator complexes. Promotes the formation of stable high-order complexes of SRF and PHOX1 and interacts cooperatively with PHOX1 to promote serum-inducible transcription of a reporter gene deriven by the C-FOS serum response element (SRE). Acts as a coregulator for USF1 by binding independently two promoter elements, a pyrimidine-rich initiator (Inr) and an upstream E-box. Required for the formation of functional ARID3A DNA-binding complexes and for activation of immunoglobulin heavy-chain transcription upon B-lymphocyte activation. [UniProt]

UniProt: P78347