Recombinant CD235a/GYPA antibody

Catalog No. ABIN7880906

This Mouse Monoclonal antibody specifically detects CD235a/GYPA in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant CD235a/GYPA antibody (ABIN7880906)

Target: CD235a/GYPA (GYPA) (Glycophorin A (GYPA))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD235a/GYPA antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RGYPA-8948

Product Details anti-CD235a/GYPA Antibody

Purpose: Glycophorin A Antibody / GYPA

Purification: Protein A/G affinity

Immunogen: A recombinant fragment of human glycophorin A protein was used as the immunogen for the Glycophorin A antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the Glycophorin A antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Glycophorin A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CD235a/GYPA

Target: CD235a/GYPA (GYPA) (Glycophorin A (GYPA))

Alternative Name: Glycophorin A

Background: Recognizes a sialoglycoprotein of 39 kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.

UniProt: P02724

Pathways: Maintenance of Protein Location