HHV 8 antibody

Catalog No. ABIN7881038

This Rat Monoclonal antibody specifically detects HHV 8 in ELISA, IF and IHC (p). It exhibits reactivity toward Herpes Simplex Virus (HSV).

Quick Overview for HHV 8 antibody (ABIN7881038)

Target: HHV 8

Reactivity: Herpes Simplex Virus (HSV)

Host: Rat

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: LN53

Product Details

Purpose: HHV8 Antibody / Herpes Virus 8 (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: Recombinant protein corresponding to the latent nuclear antigen 1 molecule of HHV8 was used as the immunogen for this HHV8 antibody.

Isotype: IgG2c, kappa

Application Details

Application Notes: Optimal dilution of the human HHV8 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the human HHV8 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details

Target: HHV 8

Alternative Name: HHV8

Target Type: Viral Protein

Background: HHV 8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients, kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. HHV 8 is the likely etiological agent of Kaposis sarcoma.