HHV 8 antibody

Catalog No. ABIN7881039

The Rat Monoclonal anti-HHV 8 antibody is suitable to detect HHV 8 in samples from Herpes Simplex Virus (HSV). It has been validated for ELISA, IF and IHC (p).

Quick Overview for HHV 8 antibody (ABIN7881039)

Target: HHV 8

Reactivity: Herpes Simplex Virus (HSV)

Host: Rat

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: LN53

Product Details

Purpose: HHV8 Antibody / Herpes Virus 8

Purification: Protein G affinity chromatography

Immunogen: Recombinant protein corresponding to the latent nuclear antigen 1 molecule of HHV8 was used as the immunogen for this HHV8 antibody.

Isotype: IgG2c, kappa

Application Details

Application Notes: Optimal dilution of the human HHV8 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the human HHV8 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details

Target: HHV 8

Alternative Name: HHV8

Target Type: Viral Protein

Background: HHV 8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients, kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. HHV 8 is the likely etiological agent of Kaposis sarcoma.