The Rabbit Monoclonal anti-HIST1H1C antibody (Clone AEDF-8) (ABIN7881058) specifically detects HIST1H1C in WB.
The antibody is reactive with Human, Mouse and Rat samples.
Optimal dilution of the Histone H1.2 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Buffer
Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store the Histone H1.2 antibody at -20oC.
Target
HIST1H1C
(Histone Cluster 1, H1c (HIST1H1C))
Alternative Name
Histone H1.2
Background
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. The HIST1H1C gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. [RefSeq]