HYAL1 antibody

Catalog No. ABIN7881137

This Rabbit Polyclonal antibody specifically detects HYAL1 in WB. It exhibits reactivity toward Mouse and Rat.

Quick Overview for HYAL1 antibody (ABIN7881137)

Target: HYAL1 (Hyaluronidase-1 (HYAL1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HYAL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HYAL1 Antibody

Purpose: Hyaluronidase 1 Antibody / HYAL1

Sequence: ASLVTHLAHT FQDIKAAMPE PD

Purification: Affinity purified

Immunogen: Amino acids ASLVTHLAHTFQDIKAAMPEPD from the mouse protein were used as the immunogen for the Hyaluronidase 1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Hyaluronidase 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Hyaluronidase 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for HYAL1

Target: HYAL1 (Hyaluronidase-1 (HYAL1))

Alternative Name: Hyaluronidase 1

Background: Hyaluronidase 1, also known as HYAL1 or LUCA1, is an enzyme that in humans is encoded by the HYAL1 gene. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is though to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency.

UniProt: Q91ZJ9

Pathways: Glycosaminoglycan Metabolic Process