HSD17B3 antibody

Catalog No. ABIN7881142

The Rabbit Polyclonal anti-HSD17B3 antibody (ABIN7881142) specifically detects HSD17B3 in WB and FACS. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for HSD17B3 antibody (ABIN7881142)

Target: HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD17B3 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-HSD17B3 Antibody

Purpose: 17-beta-HSD 3 Antibody / HSD17B3

Sequence: NLLPSHFLNA PDEIQSLIH

Purification: Antigen affinity purified

Immunogen: Amino acids NLLPSHFLNAPDEIQSLIH were used as the immunogen for the 17-beta-HSD 3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the 17-beta-HSD 3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the 17-beta-HSD 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for HSD17B3

Target: HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

Alternative Name: 17-beta-HSD 3

Background: 17beta-Hydroxysteroid dehydrogenase 3 (17b-HSD3) is an enzyme that in humans is encoded by the HSD17B3 gene and is involved in androgen steroidogenesis. This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.

UniProt: P37058

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis