Recombinant IMP3 antibody

Catalog No. ABIN7881164

This Rabbit Monoclonal antibody specifically detects IMP3 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant IMP3 antibody (ABIN7881164)

Target: IMP3 (IMP3, U3 Small Nucleolar Ribonucleoprotein (IMP3))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IMP3 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: IMP3-8985R

Product Details anti-IMP3 Antibody

Purpose: Recombinant IMP3 Antibody / Insulin like growth factor 2 mRNA binding protein 3

Purification: Protein A/G affinity

Immunogen: A recombinant fragment of human protein was used as the immunogen for the recombinant IMP3 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the recombinant IMP3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the recombinant IMP3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for IMP3

Target: IMP3 (IMP3, U3 Small Nucleolar Ribonucleoprotein (IMP3))

Alternative Name: IMP3

Background: Imp3, also known as BRMS2, C15orf12 or MRPS4, is a 184 amino acid protein that contains one S4 RNA-binding domain and is the mammalian homolog of the yeast Imp3 protein. Localized to the nucleus, Imp3 exists as a component of a heterotrimeric complex consisting of MPP10, Imp3 and Imp4 and, in this complex, plays a key role in early cleavage events during pre-18S ribosomal processing. The gene encoding Imp3 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3 % of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

UniProt: Q9NV31