CD51 antibody

Catalog No. ABIN7881192

The Rabbit Monoclonal anti-CD51 antibody is suitable to detect CD51 in samples from Human. It has been validated for WB.

Quick Overview for CD51 antibody (ABIN7881192)

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD51 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: CCE-9

Product Details anti-CD51 Antibody

Purpose: Integrin alpha V Antibody / ITGAV / Vitronectin Receptor

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Integrin alpha V / ITGAV was used as the immunogen for the Integrin alpha V antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Integrin alpha V antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the Integrin alpha V antibody at -20oC.

Target Details for CD51

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Alternative Name: Integrin alpha V

Background: The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [RefSeq]

UniProt: P06756

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex