IFITM1 antibody

Catalog No. ABIN7881249

The Rabbit Polyclonal anti-IFITM1 antibody is suitable to detect IFITM1 in samples from Human. It has been validated for WB.

Quick Overview for IFITM1 antibody (ABIN7881249)

Target: IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFITM1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IFITM1 Antibody

Purpose: IFITM1 Antibody

Sequence: VTVYHIMLQI IQEKRGY

Purification: Affinity purified

Immunogen: Amino acids VTVYHIMLQIIQEKRGY from the human protein were used as the immunogen for the IFITM1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the IFITM1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the IFITM1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for IFITM1

Target: IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))

Alternative Name: IFITM1

Background: Interferon-induced Transmembrane Protein 1(IFITM1), also called Interferon-induced Protein 17 (IFI17). IFITM1 activity is required for primordial germ cells (PGCs) transit from the mesoderm into the endoderm, and that it appears to act via a repulsive mechanism, such that PGCs avoid Ifitm1-expressing tissues. It is mapped to Chr.11 and belongs to the family of interferon-induced transmembrane proteins(Ifitm/mil/fragilis), which encodes cell surface proteins that may modulate cell adhesion and influence cell differentiation. Interferon-inducible membrane proteins of approximately 17 kDa have been suggested to play a role in the antiproliferative activity of interferons based on their pattern of induction in interferon-sensitive and -resistant cell lines and the ability of a membrane fraction enriched in 17- kDa proteins to inhibit cell growth.

UniProt: P13164