KRT15 antibody
Quick Overview for KRT15 antibody (ABIN7881365)
Target
See all KRT15 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Keratin 15 Antibody / Cytokeratin 15
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Purification
- Protein G affinity chromatography
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Immunogen
- Recombinant human KRT15 protein was used as the immunogen for the CK15 antibody.
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Isotype
- IgG2b, kappa
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Application Notes
- Optimal dilution of the Keratin 15 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store the Keratin 15 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- KRT15 (Keratin 15 (KRT15))
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Alternative Name
- Keratin 15
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Background
- Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma (BCC) and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceous. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins.
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UniProt
- P19012
Target
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