The Rabbit Monoclonal anti-Laminin beta 1 antibody (Clone AODF-12) (ABIN7881458) specifically detects Laminin beta 1 in WB.
The antibody is reactive with Human samples.
Optimal dilution of the LAMB1 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Buffer
Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store the LAMB1 antibody at -20oC.
Target
Laminin beta 1 (LAMB1)
(Laminin, beta 1 (LAMB1))
Alternative Name
LAMB1
Background
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Involved in the organization of the laminar architecture of cerebral cortex. It is probably required for the integrity of the basement membrane/glia limitans that serves as an anchor point for the endfeet of radial glial cells and as a physical barrier to migrating neurons. Radial glial cells play a central role in cerebral cortical development, where they act both as the proliferative unit of the cerebral cortex and a scaffold for neurons migrating toward the pial surface. [UniProt]