MASP2 antibody

Catalog No. ABIN7881549

This Rabbit Polyclonal antibody specifically detects MASP2 in WB and FACS. It exhibits reactivity toward Human.

Quick Overview for MASP2 antibody (ABIN7881549)

Target: MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MASP2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-MASP2 Antibody

Purpose: MASP2 Antibody

Sequence: EAGQYGVYTK VINYIPWIEN IISDF

Purification: Affinity purified

Immunogen: Amino acids EAGQYGVYTKVINYIPWIENIISDF from the human protein were used as the immunogen for the MASP2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MASP2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the MASP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for MASP2

Target: MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))

Alternative Name: MASP2

Background: Mannan-binding lectin serine protease 2 is a protein that in humans is encoded by the MASP2 gene. This gene is mapped to 1p36.22. This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

UniProt: O00187

Pathways: Complement System