MC4R antibody

Catalog No. ABIN7881586

The Rabbit Polyclonal anti-MC4R antibody is suitable to detect MC4R in samples from Human, Rat and Mouse. It has been validated for WB, IF, IHC (p) and FACS.

Quick Overview for MC4R antibody (ABIN7881586)

Target: MC4R (Melanocortin 4 Receptor (MC4R))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MC4R antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-MC4R Antibody

Purpose: MC4-R Antibody / MC4R / Melanocortin Receptor 4

Sequence: QELRKTFKEI ICCYPLGGLC DLSSRY

Purification: Affinity purified

Immunogen: Amino acids QELRKTFKEIICCYPLGGLCDLSSRY from the human protein were used as the immunogen for the MC4-R antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MC4-R antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the MC4-R antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for MC4R

Target: MC4R (Melanocortin 4 Receptor (MC4R))

Alternative Name: MC4-R

Background: Melanocortin receptor 4 is a protein that in humans is encoded by the MC4R gene. This gene is mapped to 18q21.32. The protein encoded by this gene is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity.

UniProt: P32245

Pathways: Hormone Transport, cAMP Metabolic Process, Feeding Behaviour