MAT1A antibody

Catalog No. ABIN7881623

The Rabbit Polyclonal anti-MAT1A antibody (ABIN7881623) specifically detects MAT1A in WB. The antibody is reactive with Mouse and Rat samples.

Quick Overview for MAT1A antibody (ABIN7881623)

Target: MAT1A (Methionine Adenosyltransferase I, alpha (MAT1A))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAT1A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAT1A Antibody

Purpose: Mat1a Antibody / Methionine adenosyltransferase 1

Sequence: DYQRVVRDTI KHIGYDD

Purification: Antigen affinity purified

Immunogen: Amino acids DYQRVVRDTIKHIGYDD were used as the immunogen for the MAT1A antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MAT1A antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the MAT1A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for MAT1A

Target: MAT1A (Methionine Adenosyltransferase I, alpha (MAT1A))

Alternative Name: Mat1a

Background: S-adenosylmethionine synthase isoform type-1 / Methionine adenosyltransferase 1 catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency.

UniProt: Q91X83

Pathways: Mitotic G1-G1/S Phases, M Phase, Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process