Recombinant MRPL11 antibody

Catalog No. ABIN7881646

The Rabbit Monoclonal anti-MRPL11 antibody is suitable to detect MRPL11 in samples from Human. It has been validated for WB, IHC, IF and ICC.

Quick Overview for Recombinant MRPL11 antibody (ABIN7881646)

Target: MRPL11 (Mitochondrial Ribosomal Protein L11 (MRPL11))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MRPL11 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: 32M78

Product Details anti-MRPL11 Antibody

Purpose: MRPL11 Antibody / Mitochondrial ribosomal protein L11

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human MRPL11 was used as the immunogen for the MRPL11 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MRPL11 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the MRPL11 antibody at -20oC.

Target Details for MRPL11

Target: MRPL11 (Mitochondrial Ribosomal Protein L11 (MRPL11))

Alternative Name: MRPL11

Background: MRPL11 antibody recognizes mitochondrial ribosomal protein L11, a component of the 39S large ribosomal subunit. MRPL11 contributes to mitochondrial protein synthesis by aiding translation of mRNAs encoded within mitochondrial DNA. Proper function of MRPL11 is essential for oxidative phosphorylation and maintenance of cellular energy metabolism.

Research with MRPL11 antibody has shown that altered expression of mitochondrial ribosomal proteins can impair respiratory chain activity, leading to mitochondrial dysfunction. Such disturbances are implicated in neuromuscular disorders, metabolic syndromes, and age-related decline in mitochondrial efficiency. MRPL11 expression is therefore of interest for studies of energy balance and disease pathogenesis.

Antibodies against MRPL11 are validated for use in western blot, immunohistochemistry, and immunofluorescence. These reagents help researchers analyze mitochondrial translation and investigate how ribosomal proteins contribute to cellular stress adaptation.

NSJ Bioreagents offers this MRPL11 antibody to support studies of mitochondrial protein synthesis and energy metabolism.

UniProt: Q9Y3B7