MADCAM1 antibody

Catalog No. ABIN7881684

This Rabbit Polyclonal antibody specifically detects MADCAM1 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for MADCAM1 antibody (ABIN7881684)

Target: MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MADCAM1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MADCAM1 Antibody

Purpose: MADCAM1 Antibody

Sequence: QEEEEEPQGD EDVLFRVTER WRL

Purification: Affinity purified

Immunogen: Amino acids QEEEEEPQGDEDVLFRVTERWRL from the human protein were used as the immunogen for the MADCAM1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MADCAM1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the MADCAM1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for MADCAM1

Target: MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))

Alternative Name: MADCAM1

Background: MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1), also known as MACAM1, is a protein that in humans is encoded by the MADCAM1 gene. By PCR-based analysis of somatic cell hybrids, this gene is mapped to chromosome 19. The protein encoded by this gene is an endothelil cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4 / beta7), L-selectin, and VLA-4 (alpha4 / beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin superfamily and is similar to ICAM-1 and VCAM-1.

UniProt: Q13477