MAL antibody

Catalog No. ABIN7881698

The Rabbit Polyclonal anti-MAL antibody (ABIN7881698) specifically detects MAL in WB. The antibody is reactive with Human samples.

Quick Overview for MAL antibody (ABIN7881698)

Target: MAL (Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAL Antibody

Purpose: MAL Antibody / Myelin and lymphocyte protein

Sequence: HAVFSLIRWK SS

Purification: Affinity purified

Immunogen: Amino acids HAVFSLIRWKSS from the human protein were used as the immunogen for the MAL antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MAL antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the MAL antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for MAL

Target: MAL (Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL))

Alternative Name: MAL

Background: Myelin and lymphocyte protein is a protein that in humans is encoded by the MAL gene. The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3.

UniProt: P21145

Pathways: Asymmetric Protein Localization